This report quantifies the digital therapeutics (DTx) market for chronic diseases across Europe and Portugal (2025–2030), focusing on reimbursement models, clinical adoption barriers, and patient outcomes. We size the market for chronic conditions (diabetes, hypertension, COPD, mental health) and explore how value-based care, health technology assessments (HTA), and regional reimbursement policies influence patient access and treatment duration. By 2030, the market value grows from €3.1B to €11.2B (CAGR 28%), with Portugal expanding adoption as national eHealth frameworks enable easier integration into care protocols. Outcomes show improved adherence (+22%), reduced hospitalizations (−18%), and clinical efficiency gains (−30%) as a result of digital therapeutic interventions.